Ghost Recon begins in April 2008, with civil unrest in Russia. Ultra-nationalists have seized power with plans to rebuild the Soviet Union. Their first step is clandestine support of rebel forces inGeorgia and the Baltic States. Alarmed by the threat, the U.S. deploys the Ghosts into Georgia to stop the Russians. Over the course of the campaign, the Ghosts take the fight to the ultra-nationalists, with a final showdown in Moscow's Red Square.
The game is set in New York City, where a virulent plague known as Blacklight is spreading through Manhattan. Those infected are mutated into hideous monsters of varying form, with an uncontrollable rage to kill all uninfected life-forms and a military black operations force called Blackwatch has been deployed to keep the infection from spreading. At the center of it is the protagonist, Alex Mercer, an incredibly powerfulshapeshifter with no memory of his past. Parallel to the game's storyline is the ability to play the game as a sandbox-style video game giving the player freedom to roam Manhattan.